Datarock, Soft Toy Emergency, Polly Scattergood and General Fiasco are among the latest acts confirmed for The Great Escape.
Tucker, Thomas Dybdahl, Swarathma, Indigo Children and Wintersleep have also been announced along with The John Steel Singers, British India, The Shiny Brights and Cloud Control.
There will also be performances from Lawrence Arabia, I Heart Hiroshima, Gurrumul, Noise-niks and Riddim Saunter as well as We Are Wolves, Duchess Says and Ultimate Power Duo.
Organisers have also confirmed I Was A King, Tommy Tokyo And Starving For My Gravy, The Deer Tracks, Dag For Dag, The Bewitched Hands On Top Of Our Heads, Pure Reason Revolution, Naive New Beaters and Banjo Or Freakout.
Smoke Fairies, The RGBs, Riot Lights, Rebekah Higgs, Perfect People, Pocket Lips and Punch And The Apostles have also been announced for the Brighton event along with Triggerfinger and Black Box Revelation.
Cuchillo, Mane, Racoon, The She Creatures, Adam Freeland, Phantom Limb, The Voluntary Butler Scheme, Villagers, The Tallest Man On Earth and Tom Allalone And The 78s complete the latest line-up additions.
Kasabian, The Maccabees, British Sea Power and many more will also take part.
Click here for the latest Great Escape line-up.
The Great Escape 2009 will take place at various venues around Brighton, West Sussex from 14-16 May.
Tickets are already on sale priced at £39.50 for a festival wristband, which will give festival-goers access to all venues, subject to capacity.
Click here to buy The Great Escape tickets.
The festival is back for its fourth year with 300 of the world’s best new bands set to rock 34 venues over the weekend.