Alternative club DJ's Lets Go Crazy will curate a stage at Victoria Park for Deadmau5's largest ever outdoor show.
Fronted by Callum Negus Fancey, they will host their own arena at the event taking place on June 11.
Lets Go Crazy have previously organised events at the Ministry of Sound and Bestival Festival.
Also confirmed for the concert are Nero, Zane Lowe and a DJ set from Mark Ronson.
Tickets are on sale now and priced at £42.