Black Lips, Jamie XX and Wave Machines make up the first announcement for Liverpool Sound City.
SBTRKT, The Whip, Spank Rock and Willy Mason were also confirmed for the music and arts festival that takes place across a handful of the city's finest venues from 19-21 May.
The Maccabees, The Fall and Virtual Festivals' Ones to Watch Everything Everything have played previous Liverpool Sound City events.
Sound of Guns have already been confirmed for Liverpool Sound City 2011.
Liverpool Sound City 2011 tickets are available now at £35 for a three day wristband pass or £120 for a full delegate pass.